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Every day veterinarians in practice are asked to treat pets exhibiting problem behaviors. In the last several years pharmacologic treatments of behavior have made significant advances and can serve as a critical part of therapy. Veterinary Pscyhopharmacology is a complete source of current knowledge on the subject of pharmacologic behavior modification that veterinarians can turn to for the answers they need. Classification of disorders is eschewed in favor of in-depth explanations of pharmacologic options in inducing behavior changes. Special emphasis is given to explaining the underlying mechanism of pharmacologic agents used in therapy; thus, veterinarians will know not only which drugs to prescribe but why they should be prescribed and how they work. Veterinary behaviorists, their students and residents, veterinary practitioners of all levels, and veterinary students will find this book invaluable in providing information about their patients' behavior problems and the psychoactive medications that might help them.
Handbook of Essential Psychopharmacology, Second Edition, provides an indispensable guide to vital information in the rapidly expanding field of psychopharmacology. The updated edition of this popular handbook will continue to be a reference that is simply the essential starting point in psychopharmacology for residents and experienced clinicians alike. Busy residents and clinicians will find a quick, current, and accessible guide to basic facts about psychotropic drugs, including dosages, indications, and drug interactions. As in the first edition, its structure is clear and easy to read, including An all-new introductory chapter, designed to equip the reader with a basic understanding of pharmacodynamics and pharmacokinetics Four main chapters covering the four main groups of psychotropic medications: antidepressants, antipsychotics, anxiolytics, and mood stabilizers A consistent format for all four chapters that summarizes critical information about each group of medications, including drug class, indications, mechanisms of action, pharmacokinetics, main side effects, drug-drug interaction, potentiating maneuvers, and use in special populations A wealth of tables and graphs for quick clinical consultation and unique self-instruction sets of questions and answers Fascinating and educational vignettes and puzzlers, extensive references for further reading, and -- new to this edition -- an invaluable appendix of fifty questions and answers, designed to test the reader's knowledge and comprehension of the text Densely informative and packed with practical material and special features, this truly essential guide is a handy clinical reference for experienced clinicians, an ideal teaching tool for educators, and a useful resource for residents, especially those preparing for the psychiatry board examinations.
The fact that tobacco ingestion can affect how people feel and think has been known for millennia, placing the plant among those used spiritually, honori?cally, and habitually (Corti 1931; Wilbert 1987). However, the conclusion that nicotine - counted for many of these psychopharmacological effects did not emerge until the nineteenth century (Langley 1905). This was elegantly described by Lewin in 1931 as follows: “The decisive factor in the effects of tobacco, desired or undesired, is nicotine. . . ”(Lewin 1998). The use of nicotine as a pharmacological probe to und- stand physiological functioning at the dawn of the twentieth century was a landmark in the birth of modern neuropharmacology (Limbird 2004; Halliwell 2007), and led the pioneering researcher John Langley to conclude that there must exist some “- ceptive substance” to explain the diverse actions of various substances, including nicotine, when applied to muscle tissue (Langley 1905). Research on tobacco and nicotine progressed throughout the twentieth century, but much of this was from a general pharmacological and toxicological rather than a psychopharmacological perspective (Larson et al. 1961). There was some attention to the effects related to addiction, such as euphoria (Johnston 1941), tolerance (Lewin 1931), and withdrawal (Finnegan et al. 1945), but outside of research supported by the tobacco industry, addiction and psychopharmacology were not major foci for research (Slade et al. 1995; Hurt and Robertson 1998; Henning?eld et al. 2006; Henning?eld and Hartel 1999; Larson et al. 1961).
Describes the latest advances in psychopharmacology - one of the most rapidly developing fields in modern science. This latest edition has been updated to cover new developments in drug therapy and research including newly introduced antipsychotics, antidepressants and antidementia drugs. Sections on the treatment of depression and dementia have been revised to include new developments in treatment strategies. It will be welcomed for its essentially clinical and psychological approach to modern pharmaceuticals, their therapeutic uses and limitations, adverse reactions and future directions for research.
Psychopharmacology, Volume 2: Preclinical Psychopharmacology presents the mechanism of action of antidepressant drugs and neuroleptics. This book discusses the significance of the interaction between various neurotransmitter system in both biochemical and functional consequences of repeated drug administration. Organized into 12 chapters, this volume begins with an overview of the effects of antidepressant drugs on norepinephrine metabolism. This text then discusses the different aspects of monoamine oxidase and its inhibitors. Other chapters consider the mechanism of action of lithium, which requires consideration of some of the general characteristics of periodic behavior. This book discusses as well the preclinical aspects of tranquilizers, particularly those dealing with benzodiazepines and non-benzodiazepines acting through the benzodiazepine receptor. The final chapter deals with the various behavioral and electrophysiological effects of cocaine in animals, which presumably reflect both local anesthetic properties and action on monoamine mechanisms. This book is a valuable resource for neuropharmacologists and practicing psychiatrists.
The first six volumes of the Handbook reviewed basic neuropharmacology, drawing on expertise in biochemistry, pharmacology and electrophysiology. The next three volumes focus attention on the functional importance of these basic neuropharmacological mechanisms for normal behavior. In order to study this interface in the intact functioning organism, appropriate methods for describing and quantifying behavior must be developed. The past twenty years have witnessed a revolution in the study of behavior which has taken us away from the often fruitless theoretical arguments to descriptive behaviorism. Technical achievements in the design of apparatus and the recording of behavior played an important role in these developments, and the resultant behavioral methods have been accepted and found useful in studying the effects of drugs. The development of psycho pharmacology as a discipline owes as much to these behavioral methods as it does to the basic neuropharmacological techniques pioneered for in vitro studies. In the first section of Volume 7, an effort has been made to provide reviews both of theory and practice in behavioral science. Milner's chapter deals with the concept of motivation in a theoretical framework. By contrast, the chapters by Morse et al. and Dews and DeWeese provide a more descriptive view of the various ways in which aversive stimuli control behavior and the importance of schedules of reinforcement in determining the profile of responding in the animal. The equal importance of observational behav ioral methods is well illustrated by Mackintosh et al.
Volume 15 of Handbook of Psychopharmacology represents the first of a new series of volumes whose aim is to bring earlier sections of the work up to date by describing the latest developments in the field. It is now seven years since the first Handbook volumes on Basic Neuropharmacology were published, and there have been many important advances. As in many other areas in science, progress in this field has depended to a considerable extent on the availability of new experimental methods, and Volume 15 reviews some major recent developments, including new autoradiographic techniques that allow direct visualization of drug and transmitter receptors in the nervous system, and the pinpointing of the precise locations of the changes in brain metabolism elicited by various drug treatments. Volumes 16 and 17 will cover two of the most active areas for basic research in psychopharmacology at the moment: the characterization of drug and transmitter receptors in brain by radioligand binding techniques, and studies of the role of small peptides in brain function. The latter area, in particular, illustrates how rapidly progress continues to be made in basic research on the mechanisms of chemical communication within the nervous system. Seven years ago when the Handbook first appeared none of the opioid peptides (enkephalins and endorphins) had yet been identified. Since then a whole new area of basic biological research has focused on these substances, and in addition we know of more than thirty other neuropeptides with putative eNS transmitter functions.
A study focusing on what is now understood about the basic mechanisms underlying addiction, with a look at the psychological and social dimensions of the various forms of addiction discussed.
Volume 6 of this invaluable series encompasses the increasing range of issues associated with psychopharmacology, giving up-to-date information not only on the scientific aspects of the subject but also on the social, legal and ethical implications. Chapters include: Stress, glucocorticoids and depression?implications for pharmacological intervention Pharmacovigilance and antidepressants Quality of life in psychopharmacology?what are we measuring and why does it matter? Legal aspects of drugs in the workplace Cognitive testing of new anticonvulsants Human Psychopharmacology: Measures and Methods has become established as a standard text in the subject, providing clear and authoritative treatments of the important and current issues in psychopharmacology. This volume will be an invaluable reference point for all those working in the area.
An affordable, practical guide to prescribing psychiatric drugs to the pediatric patient. Emphasizes the unique issues involved in treating children and teens. Provides the reader with the special knowledge necessary for the optimal psychopharmacologic treatment of these patients. Incorporates up-to-date information on efficacy, side effects, and drug metabolism. Discusses the basic types of baseline assessments--diagnostic, medical, symptomatic, functional, and more--that are necessary to initiate psychopharmacologic treatment. Covers fundamental principles of treatment such as models of care, selection of pharmaceutical agents, therapeutic drug monitoring, education strategies, and dealing with refractory cases. Describes, step by step, how to initiate, monitor, evaluate, improve, or change treatment according to the type of diagnosis or patient problem. Includes an appendix that explains how to set up a psychopharmacologic treatment clinic and lists a variety of assessment instruments that are useful in everyday practice.
- Author : Michael R. Trimble
- Publisher : Oxford University Press, USA
- Release Date : 1986
- Genre : Social Science
- Pages : 134
- ISBN : UOM:39015010167867
This book explores the use in psychopharmacology of the new brain imaging techniques, including Positron Emission Tomography (PET) and Magnetic Resonance Imaging (MRI). Delivered at a symposium sponsored by the British Association for Psychopharmacology, these ten papers consider the underlying principles of the new imaging techniques and weigh their potential use in the study of psychotropic drugs, particularly the effect of these drugs on the central nervous system. The papers are complemented with numerous illustrations, including four full-color plates.